abstract：:The endogenous cycle of Eimeria flavescens was studied in specific pathogen-free rabbits by means of histology and transmission electron microscopy. In total, five asexual generations were observed and two types of meronts and merozoites were found in each generation. Type A gave rise to a smaller number of thick poly...

journal_title：Parasitology research

authors： Pakandl M,Cerník F,Coudert P

更新日期：2003-10-01 00:00:00

abstract：:Light, scanning and transmission electron microscope examinations of adult Cystidicoloides ephemeridarum nematodes, parasitic in the stomach of brown trout (Salmo trutta fario L.), revealed that the body wall is composed of a cuticle, a hypodermis and longitudinally oriented somatic musculature. The body cuticle is co...

journal_title：Parasitology research

authors： Frantová D,Moravec F

更新日期：2003-09-01 00:00:00

abstract：:Radiological features and biochemical changes were investigated during the parenchymal and ductal phases of chronic Fasciola hepatica infection in sheep. The activities of plasma aspartate aminotransferase (AST), lactate dehydrogenase (LDH) and gamma-glutamyl transpeptidase (GGT), plasma levels of IgG anti- F. hepatic...

journal_title：Parasitology research

authors： Gonzalo-Orden M,Millán L,Alvarez M,Sánchez-Campos S,Jiménez R,González-Gallego J,Tuñón MJ

更新日期：2003-08-01 00:00:00

abstract：:Hassalstrongylus epsilon is a small nematode, whose adult forms are found among the intestinal microvilli of the water rat Nectomys squamipes, Brants 1827 (Rodentia: Muridae). The external appearance of the cuticle, which presents transversal striations and longitudinal ridges, is described using scanning electron mic...

journal_title：Parasitology research

authors： Oliveira-Menezes A,De Souza W,Lanfredi RM

更新日期：2003-07-01 00:00:00

abstract：:Infection in dogs and humans with the protozoan parasite Leishmania are widespread in tropical and subtropical countries around the globe. Sand flies of the order Phlebotomus in the Old World and Lutzomyia in the New World function as the vector of this disease. In dogs, skin lesions are the most prominent signs of ca...

journal_title：Parasitology research

authors： Mencke N,Volf P,Volfova V,Stanneck D

更新日期：2003-07-01 00:00:00

abstract：:The discovery and optimization of antiparasitic compounds has profited by information-based methods newly emerged in the modern drug development process. The generation of computer models enables the cost-efficient and fast computational screening of virtual compound libraries for biologically active molecules. Two so...

journal_title：Parasitology research

authors： Wolf K,Dormeyer M

更新日期：2003-06-01 00:00:00

abstract：:Amebic cysteine protease 2 (EhCP2) was purified from ethyl ether extracts of axenically grown trophozoites of Entamoeba histolytica strain HM1-IMSS. The purification procedure involved molecular filtration and electroelution. Sequence analysis of the purified product revealed EhCP2 and ubiquitin(s). Electrophoretic mi...

journal_title：Parasitology research

authors： Olivos-García A,González-Canto A,López-Vancell R,García de León Mdel C,Tello E,Nequiz-Avendaño M,Montfort I,Pérez-Tamayo R

更新日期：2003-06-01 00:00:00

abstract：:Intraspecific and interspecific effects on the growth and body size of helminths are rarely studied in natural situations, yet knowing what determines helminth sizes and thus fecundity is crucial to our understanding of helminth ecology and epidemiology. The determinants of average individual worm mass were investigat...

journal_title：Parasitology research

authors： Poulin R,Giari L,Simoni E,Dezfuli BS

更新日期：2003-06-01 00:00:00

abstract：:A new method for the experimental production of necrotic enteritis in chickens is described. The main features are the use of a diet high in wheat and fish meal content; oral administration of a non-lethal inoculum of the coccidium Eimeria maxima followed 6 days later by the bacterium Clostridium perfringens type A pe...

journal_title：Parasitology research

authors： Williams RB,Marshall RN,La Ragione RM,Catchpole J

更新日期：2003-05-01 00:00:00

abstract：:Micronemes are characteristic secretory organelles located within the apical cell region of apicomplexan parasites. The protein contents are exocytosed during an early phase of host cell invasion and contribute to parasite motility and the invasion of target cells. We report here on the cloning and heterologous expres...

journal_title：Parasitology research

authors： Klein H,Mueller S,Loeschner B,Toenjes RR,Braun G,Mueller EC,Otto A,Montag T

更新日期：2003-05-01 00:00:00

abstract：:Chagas' disease, which is an important health problem in humans, is caused by the protozoan Trypanosoma cruzi. The cellular and molecular mechanisms, involved in the selective tropism of T. cruzi to different organs remain largely unknown. In this study we designed a PCR-based molecular diagnosis method in order to st...

journal_title：Parasitology research

authors： Vera-Cruz JM,Magallón-Gastelum E,Grijalva G,Rincón AR,Ramos-García C,Armendáriz-Borunda J

更新日期：2003-04-01 00:00:00

abstract：:Paramyosin is a muscle protein that probably plays a role in the survival of the larval stage of Taenia solium during its prolonged host-parasite relationship. Here we describe the structure of the gene coding for the paramyosin of T. solium. The characterization of two clones obtained from a genomic library showed th...

journal_title：Parasitology research

authors： Vargas-Parada L,Laclette JP

更新日期：2003-03-01 00:00:00

abstract：:A total of 37 juvenile Etmopterus spinax from the Norwegian Deep were examined for stomach contents and metazoan ecto- and endoparasites. These squaliform elasmobranchs were caught by benthopelagic net in May 2001 at a depth of 194-214 m. The euphausiid Meganyctiphanes norvegica and the teleost Maurolicus muelleri wer...

journal_title：Parasitology research

authors： Klimpel S,Palm HW,Seehagen A

更新日期：2003-03-01 00:00:00

abstract：:Molecular karyotypes that revealed size polymorphisms between homologous forms of chromosomes 1, 2, 3 or 4 in three strains of the coccidial parasite Eimeria tenella were derived by pulsed field gel electrophoresis (PFGE) using brands of agaroses marketed either specifically for PFGE or for purposes such as protein el...

journal_title：Parasitology research

authors： Sheriff R,Carroll F,Shirley MW

更新日期：2003-03-01 00:00:00

abstract：:The paucity of human cell lines expressing defined receptors for the cytoadhesion of erythrocytes infected with the human malarial parasite Plasmodium falciparumhas hampered the investigation of this important virulence property. Here, we investigate a permanent cell line derived from a human, malignant schwannoma, te...

journal_title：Parasitology research

authors： Andrews KT,Viebig NK,Wissing F,Klatt N,Oster N,Wickert H,Knolle P,Lanzer M

更新日期：2003-02-01 00:00:00

abstract：:Biomphalaria glabrataembryonic (Bge) cells have been shown to provide favourable environmental conditions for the development of Schistosoma mansoni sporocysts. We investigated the effect of Bge excretory-secretory products on metabolic activity and gene transcription in S. mansoni mother sporocysts. Using the differe...

journal_title：Parasitology research

authors： Coppin JF,Lefebvre C,Caby S,Cocquerelle C,Vicogne J,Coustau C,Dissous C

更新日期：2003-01-01 00:00:00

abstract：:Production of parasite-specific antibodies is an important component of immunity to blood stage malaria infection, as shown by several previous studies in rodent models. However, no study has addressed the induction of humoral immunity by different parasites in a genetically homogeneous host population. Here, levels o...

journal_title：Parasitology research

authors： Smith EC,Taylor-Robinson AW

更新日期：2003-01-01 00:00:00

abstract：:An arbitrary-primed RNA PCR differential display strategy was used to identify midgut genes of the reduviid bug Triatoma infestans that were differentially expressed after a blood meal. From interesting bands, 33 distinct cDNAs were cloned and sequenced. Although many had long open reading frames, most of the transcri...

journal_title：Parasitology research

authors： Kollien AH,Billingsley PF

更新日期：2002-12-01 00:00:00

abstract：:We assessed the cellular immunological responses to two Plasmodium falciparum liver-stage antigen (LSA)-1-derived T-cell epitopes in healthy Gabonese children and adults. The N-terminal peptide, designated T1, induced interferon (IFN)-gamma production in peripheral blood mononuclear cells (PBMC) from a significantly l...

journal_title：Parasitology research

authors： Bongartz M,Rezbach P,Borrmann S,Hollingdale MR,Kremsner PG,Luty AJ

更新日期：2002-12-01 00:00:00

abstract：:This work describes a simple method to yield large amounts of Leishmania amastigote-like forms in axenic cultures using promastigotes as the starting population. The method described induced extracellular amastigote transformation of Leishmania amazonensis (97%), Leishmania braziliensis (98%) and Leishmania chagasi (9...

journal_title：Parasitology research

authors： Teixeira MC,de Jesus Santos R,Sampaio RB,Pontes-de-Carvalho L,dos-Santos WL

更新日期：2002-11-01 00:00:00

abstract：:In murine Taenia crassiceps cysticercosis, females sustain larger intensities of infection than males. However, during chronic infection, this difference disappears and males show a feminization process. To further study the role of two cytokines, interleukin-6 (IL-6) and macrophage-migration inhibitory factor (MIF), ...

journal_title：Parasitology research

authors： Morales-Montor J,Baig S,Kabbani A,Damian RT

更新日期：2002-10-01 00:00:00

abstract：:We evaluated serum examination as an alternative to fecal analysis for the diagnosis of exposure to Cryptosporidium parvum in cattle. The accuracy of the serum ELISA was compared to the combined results of concentration flotation microscopy and fecal enzyme immunoassay. The expected performance of the serum ELISA at d...

journal_title：Parasitology research

authors： Nydam DV,Lindergard G,Guard CL,Schaaf SL,Wade SE,Mohammed HO

更新日期：2002-09-01 00:00:00

abstract：:When given orally, quinine or salinomycin cause irreversible damage to the plasmodial developmental stages of Henneguya sp., a gill parasite in the tapir fish Gnathonemus petersii. Naturally infected tapir fish measured 75-169 mm in total length and their total weight ranged over 4.3-11.7 g. The fish bore 7-77 plasmod...

journal_title：Parasitology research

authors： Dohle A,Schmahl G,Raether W,Schmidt H,Ritter G

更新日期：2002-09-01 00:00:00

abstract：:An optimized protocol is presented to visualize gene expression in the sedentary beet cyst nematode, Heterodera schachtii, by whole-mount in situ hybridization. Two different probes were used for genes with known expression pattern in other nematodes. Vacuum infiltration of the fixative significantly increased its eff...

journal_title：Parasitology research

authors： Vanholme B,De Meutter J,Tytgat T,Gheysen GD,Vanhoutte I,Gheysen GD

更新日期：2002-08-01 00:00:00

abstract：:We examined the in vitro effect of increasing gliotoxin concentrations on the infectivity of Toxoplasma gondii for NIH-3T3 murine fibroblasts and on Toxoplasma chymotrypsin-like activity, which is specific to the proteasome. Parasite penetration of host cells was not modified by a high gliotoxin concentration (1 micro...

journal_title：Parasitology research

authors： Paugam A,Creuzet C,Dupouy-Camet J,Roisin P

更新日期：2002-08-01 00:00:00

abstract：:Snake venom can affect the growth of Trypanosoma cruzi and Leishmania spp. As new classes of therapeutic drugs against protozoan parasites could be derived from snake venom, alterations in the ultrastructure and growth of the epimastigotes, trypomastigotes and amastigotes of T. cruzi, as well as the promastigotes of L...

journal_title：Parasitology research

authors： Gonçalves AR,Soares MJ,de Souza W,DaMatta RA,Alves EW

更新日期：2002-07-01 00:00:00

abstract：:The C57BL/6J strain of Mus musculus is susceptible to the terrestrial trematode Brachylaima cribbi. The duration of infection in these mice is generally 9-12 weeks with a peak excretion of eggs at 4 weeks post-infection (wpi). The effects of age and sex on the course of infection were investigated by comparing infecti...

journal_title：Parasitology research

authors： Butcher AR,Palethorpe HM,Grove DI

更新日期：2002-07-01 00:00:00

abstract：:We report on serine protease activity in cercarial secretions (CSs) from the bird parasite Trichobilharzia ocellata. Using a colorigenic substrate, the biochemical properties of this enzyme were studied and its activity was compared to the homologous one in CSs from the human parasite Schistosoma mansoni. The specific...

journal_title：Parasitology research

authors： Bahgat M,Ruppel A

更新日期：2002-06-01 00:00:00

abstract：:The efficacy of a combination of ivermectin (IVM) and albendazole (ABZ) used as a chemoprophylactic treatment and as treatment of secondary hydatidosis is described for the first time. IVM treatment alone was not effective against Echinococcus granulosus, either when the protoscolices were recently inoculated or when ...

journal_title：Parasitology research

authors： Moreno MJ,Casado N,Urrea-París MA,Rodríguez-Caabeiro F

更新日期：2002-06-01 00:00:00

abstract：:Previous studies have shown that excretory/secretory products of larval Taenia crassiceps have immunomodulatory activities. We report here that one of these products, termed p66, possesses activities that mimic some characteristics of murine interferon-gamma (IFN-gamma). Purified p66 cross-reacts with anti-murine IFN-...

journal_title：Parasitology research

authors： Spolski RJ,Thomas PG,See EJ,Mooney KA,Kuhn RE

更新日期：2002-05-01 00:00:00

abstract：:Two species of Babesia were isolated from naturally infected sheep in the eastern part of Gansu province. One of the species was identified as B. ovis, while the another one seems as yet to be an unidentified Babesia species. The latter could be transmitted transovarially by Haemaphysalis longicornis. It was shown tha...

journal_title：Parasitology research

authors： Bai Q,Liu G,Liu D,Ren J,Li X

更新日期：2002-05-01 00:00:00

abstract：:A good CD8+ response is required for immunity to many intracellular pathogens. Traditional antigen delivery using isolated sub-units or killed pathogens and adjuvant stimulates strong antibody responses but weak T-cell reactivity. Attenuated vaccines are usually more effective. The prime-boost delivery system based on...

journal_title：Parasitology research

authors： Hall R,Adamson R,Boulter N

更新日期：2002-05-01 00:00:00

abstract：:Amastigotes of Leishmania species belonging to the Leishmania mexicana complex exhibit large lysosomes, called megasomes, which are rich in cysteine proteinases. Various aspects of the host-parasite interaction, the differentiation process as well as intracellular survival, have been attributed to these proteinases. T...

journal_title：Parasitology research

authors： Ueda-Nakamura T,da Conceição Rocha Sampaio M,Cunha-e-Silva NL,Traub-Cseko YM,de Souza W

更新日期：2002-04-01 00:00:00

abstract：:A retrospective study was carried out on the experimental infections of Lymnaea truncatula with Fasciola hepatica performed over the last 20 years to determine if the populations of snails living in highland or lowland countries had the same ability to sustain trematode larval development. The six highland populations...

journal_title：Parasitology research

authors： Vignoles P,Favennec L,Dreyfuss G,Rondelaud D

更新日期：2002-04-01 00:00:00

abstract：:Ixodes holocyclus has a narrow, discontinuous distribution along the east coast of Australia. We studied ticks from 17 localities throughout the geographic range of this tick. The ITS2 of I. holocyclus is 793 bp long. We found nucleotide variation at eight of the 588 nucleotide positions (1.4%) that were compared for ...

journal_title：Parasitology research

authors： Shaw M,Murrell A,Barker SC

更新日期：2002-03-01 00:00:00

abstract：:Entamoeba histolytica infection in humans is still one of the leading causes of parasitic diseases among the developing countries, including India. It therefore becomes extremely important to characterize this parasite with the aim of preventing and controlling the amoebiasis which it causes. The present study describ...

journal_title：Parasitology research

authors： Prakash A,Chakraborti A,Mahajan RC,Ganguly AK

更新日期：2002-02-01 00:00:00

abstract：:We report the ultrastructural alterations induced on epimastigotes by nifurtimox and 5-nitro-2-thienyl-malononitrile (5NO2TM), a novel compound with anti-Trypanosoma cruzi activity. Parasites treated with concentrations of nifurtimox lower than usually employed for this kind of study showed vacuolisation, alterations ...

journal_title：Parasitology research

authors： Muelas-Serrano S,Pérez-Serrano J,Gómez-Barrio A,Arán VJ,Rodríguez-Caabeiro F

更新日期：2002-02-01 00:00:00

abstract：:A cyst-forming strain of Toxoplasma gondii was transfected with the Escherichia coli LacZ gene and expressed beta-galactosidase constitutively. This strain has been used to localize and analyze the early stages of development and reactivation of T. gondii in mice. The chromogenic detection of the enzyme allows an easy...

journal_title：Parasitology research

authors： Dao A,Soête M,Sergent V,Deslée D,Fortier B,Dubremetz JF

更新日期：2002-01-01 00:00:00

abstract：:Sarcocystis neurona is the parasite associated with equine protozoal myeloencephalitis (EPM). Recently, cats (Felis domesticus) have been implicated as a potential intermediate host in the life cycle of S. neurona. This study was initiated to determine whether cats have antibodies that react to S. neurona antigens sim...

journal_title：Parasitology research

authors： Turay HO,Barr BC,Caldwell A,Branson KR,Cockrell MK,Marsh AE

更新日期：2002-01-01 00:00:00

abstract：:During infections, Giardia lamblia undergoes a continuous change of its major surface antigens, the variant-specific surface proteins (VSPs). Many studies on antigenic variation have been performed using G. lamblia clone GS/M-83-H7, which expresses surface antigen VSP H7. The present study was focused on the identific...

journal_title：Parasitology research

authors： Bienz M,Siles-Lucas M,Müller N

更新日期：2001-12-01 00:00:00